Manhattan BioSolutions, Inc. was founded in 2018 by Dr. Borys Shor, an entrepreneur and biopharma veteran based in New York City, and Professor Yossef Av-Gay at the University of British Columbia in Vancouver, Canada, with a core mission to unlock the natural ability of the human innate immune system to defend the body against the invading pathogens or cancer. The initial focus of Manhattan Bio was the development of synthetic live medicines specifically designed to target the unique mutations found in cancer cells, provoking a potent and tailored immune response against the tumors. Manhattan Bio has achieved significant preclinical proof of concept data, providing compelling evidence of the efficacy and potential of this innovative approach. As the company evolved, it explored the potential of other remarkable protective mechanisms governing immune defense and homeostasis within the body, with the aim of developing novel therapeutics.
In 2018, our startup has won the prestigious Johnson & Johnson Innovation QuickFire Challenge Competition and the accompanying award, granting us free laboratory and office space at the newly opened JLabs@NYC incubator in downtown Manhattan. Since 2020, our R&D laboratory was conveniently located near the NYU campus in Manhattan, designed to support in-house pre-clinical discovery of antibodies and functional cellular assays. At the end of 2023, Manhattan Bio was honored to receive a second QuickFire “Science in the City” award sponsored by J&J Innovation, recognizing our pioneering work in biologics discovery. This award provides new state-of-the-art facilities at the JNJ JLabs, featuring cutting-edge equipment and collaborative workspaces. We will be moving to these new labs in early 2024 to accelerate translation of our programs. We also partner with Gilman Biosciences, headed by Dr. Babic, to externalize preclinical assay development, leveraging his expertise and track record in translational drug discovery.
Establishing a track record of success, Manhattan Bio has been awarded grants and awards from various prestigious organizations, including the New Jersey CSIT, the University at Buffalo Center for Advanced Technology in Big Data and Health Sciences, the National Science Foundation, the National Cancer Institute, and the New York State Center for Biotechnology at Stony Brook University, further bolstering our innovative research and development efforts.